A man with a low IQ has accomplished great things in his life and been present during significant historic events—in each case, far exceeding what anyone imagined he could do. But despite all he has achieved, his one true love eludes him.
For a long time, Natalie, an Australian architect living in New York City, had always believed that what she had seen in rom-coms is all fantasy. But after thwarting a mugger at a subway station only to be knocked out while fleeing, Natalie wakes up and discovers that her life has suddenly become her worst nightmare—a romantic comedy—and she is the leading lady.
The TV series tells the story of Rosario Tijeras (Maria Fernanda Yepez), a woman raised in a slum that was 18 years old when she was raped by a local gang, and which causes her to change for the better after her classmate was killed by a drug lord, El Papa. Rosario avenges her rape by cutting El Cache's testes with scissors (hence the name, Rosario Tijerias) and purposely goes to the market of her stepfather to get picked up to go to El Papa's house so she can execute her plan.
Gloria is a 58-year-old divorcée. Her children have all left home but she has no desire to spend her days and nights alone. Determined to defy old age and loneliness, she rushes headlong into a whirl of singles’ parties on the hunt for instant gratification – which only leads to repeated disappointment and enduring emptiness. But when Gloria meets Rodolfo, an ex-naval officer seven years her senior, she begins to imagine the possibility of a permanent relationship.